The Great Lakes-St. Lawrence region plays a pivotal role in North American trade, generating over $45.6 billion in economic activity for the U.S. and $59.2 billion for Canada. This region accounts for more than 30% of the economic activity between the two countries, highlighting its strategic importance. The waterways facilitate significant trade, impacting personal income and tax revenues. The U.S. sees $17.9 billion in personal income and $9 billion in taxes, while Canada benefits from $23.2 billion in personal income and $11.7 billion in taxes. These figures underscore the region's economic vitality and its influence on surrounding states and provinces. The data reveals a robust economic corridor, essential for trade and commerce, with substantial contributions to both nations' economies. The interplay between economic activity, personal income, and taxes illustrates the region's comprehensive impact, making it a cornerstone of U.S.-Canada economic relations. The strategic utilization of these waterways continues to drive economic growth, emphasizing the need for sustainable management and development to maintain this vital trade corridor.